What is anastrozole? Anastrozole (brand name Arimidex) is occasionally used to supplement low testosterone. This drug works by decreasing the amount of estrogen the body makes.  Effectiveness of anastrozole in men There is limited evidence for anastrozole’s effectiveness in men. In one small study, anastrozole increased testosterone in older men with mild hypogonadism (low T) (Leder, 2004). In another study […]